A native of Italy, Dr. Spagnoli received her MD at the University of Rome Tor Vergata School of Medicine where she also completed a residency in Pediatrics and was a faculty member for two years. In 1990, she was an European Community Erasmus Program Research Fellow at St. Bartholomew’s Hospital in London, and in 1992 at Stanford University as Fulbright Scholar. In 1995, Dr. Spagnoli decided to pursue her career in academic Medicine the United States and to maintain her medical credentials she repeated her residency training in Pediatrics and completed a Fellowship in Pediatric Endocrinology at the Doernbecher Children’s Hospital at Oregon Health Sciences University in Portland, Oregon. She was an Assistant Professor of Pediatrics at Oregon Health Sciences University for one year and at Vanderbilt University for six years. She was appointed in 2007, Associate Professor in Pediatrics and Biomedical Engineering at University of North Carolina at Chapel Hill. In 2008, she was awarded with the tenure by the University of North Carolina at Chapel Hill. Dr. Spagnoli is the program Director of the Fellowship Program in Pediatric Endocrinology at the University of North Carolina at Chapel Hill.
Dr. Spagnoli has almost 20 years of research experience in the bone and cartilage field. Her research focuses on discovering the ability of growth factors to control adult stem cells for tissue regeneration, and understanding the mechanisms of tissue development to empower the regenerative responses during the tissue repairing process. Her studies by simultaneously looking at stem cell biology and tissue development have represented a unique opportunity to discover and fully optimize the clinical use of adult stem cells in bone and cartilage diseases. Dr. Spagnoli has extensively published in this field. Her research has been funded by NIH and numerous other agencies and foundations. She has served as an ad hoc reviewer for several funding agencies and foundations including NIH, Health Research Board of Ireland, and Arthritis Foundation. She is also a reviewer for several scientific journals and annual meetings for bone and endocrine societies.
Dr. Spagnoli has mentored over twenty between graduate students, post-doctoral fellows and junior faculty members. She is a member of the Department of Pediatrics Faculty Mentoring Program at University of North Carolina at Chapel Hill to which she has contributed by identifying the Program goals, defining the activities and delineating the outcome indicators of Departmental mentoring success. As a member of the Division of Pediatric Endocrinology at University of North Carolina at Chapel Hill, Dr. Spagnoli provides care to children with a variety of Endocrine disorders and diabetes. She teaches fellows, medical students and graduate and undergraduate students on a daily basis on basic and translational research as well as on clinical pediatric endocrinology topics.